Title

Neuronal loss in the Prelimbic Cortex, not the Infralimbic Cortex in a mouse model of Huntington's Disease

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Julia Norton

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Presentation Type

Presentation

Faculty Sponsor

Zach Simmons & Mark Pitzer

Department

Psychological Sciences

Description

We utilized immunofluorescent techniques to investigate neuronal and glial changes in the infralimbic and prelimbic subregions of the mPFC, two regions that innervate the nucleus accumbens shell and core respectively. Results indicated significant neuronal loss in the prelimbic cortex of HD mice compared to controls at 15 weeks.

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2020 Founders' Day presentation

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Neuronal loss in the Prelimbic Cortex, not the Infralimbic Cortex in a mouse model of Huntington's Disease

We utilized immunofluorescent techniques to investigate neuronal and glial changes in the infralimbic and prelimbic subregions of the mPFC, two regions that innervate the nucleus accumbens shell and core respectively. Results indicated significant neuronal loss in the prelimbic cortex of HD mice compared to controls at 15 weeks.