Title

Defining the role of two newly identified proteins in the Vibrio vulnificus TonB2 system

Authors

Brianne R. Zbylicki
Mario Manzo
Elysse A. Phillips
Ryan J. Kenton

Date

Fall 2018

Faculty Advisor

Ryan J. Kenton

Sponsor

MJ Murdock Charitable Trust, University of Portland

College/School

College of Arts & Sciences

Department

Department of Biology

Abstract

Vibrio vulnificus is a human pathogenic bacteria that is closely related to Vibrio cholera, the disease causing agent of cholera. Three TonB transport systems are found in the outer membrane of V. vulnificus and are responsible for powering the uptake of iron bound siderophores into the cell. Within the Ton82 and TonB3 systems are two proteins, Orf1 and Orf6. The function and necessity of Orf1 and Orf6 to the TonB systems were investigated through the use of growth, motility, and antibiotic sensitivity assays and RNA transcriptional level analysis.

Subjects

Cholera; Vibrio cholerae; Vibrio vulnificus; Pathogenic bacteria

Publication Information

A Summer Research Celebration Project

© 2018 The Authors

Citation: Pilot Scholars Version (Modified MLA Style)

Zbylicki, Brianne R.; Manzo, Mario; Phillips, Elysse A.; and Kenton, Ryan J., "Defining the role of two newly identified proteins in the Vibrio vulnificus TonB2 system" (2018). Biology Undergraduate Publications, Presentations and Projects. 9.
https://pilotscholars.up.edu/bio_studpubs/9

Document Type

Student Project